From Genetic Variant to Cellular Effect
How can a change in DNA influence what happens inside a cell?
Explore the iological journey from genetic variation to gene expression, cell identity, cellular states, and disease mechanisms .
Genetic Variant
A genetic variant is a difference in DNA sequence. Researchers investigate whether a variant can influence gene regulation, gene expression, or biological function.
Gene Expression
Genes are expressed differently depending on the biological context. Studying RNA helps researchers understand which genes are active and how their expression changes.
Individual Cells
A tissue contains many different cell populations. Bulk analysis can combine these populations, while single-cell RNA sequencing allows researchers to examine gene expression in individual cells.
EMBL-EBI Single Cell Expression Atlas
Explore the Biology Behind Genetic Variation
Understanding genetic variation is only the beginning. By combining genomics with single-cell approaches, researchers can explore how genetic differences relate to gene expression, cell identity, cellular states, and disease biology. CGseq brings these concepts together to help you explore biology from the level of DNA to individual cells.
